Tex2RTF accepts two arguments (input and output filenames) and trailing (optional) switches. If both filenames are given, the utility will work in batch mode. Otherwise, a main window will be shown, will appropriate menu items for selecting input and output filenames, starting off the conversion process, and so on.
It is recommended that you run Tex2RTF twice in order to be sure of of resolving all references and including an up-to-date contents page.